Breast Imaging Technologies Market Development, Growth and Forecast to 2020
The global breast imaging technologies market is growing significantly due to technological advancement in the detection of breast cancer in the industry. Massive unexplored market in breast imaging technologies industry of developing economies are creating ample opportunities for the breast imaging technologies market to grow at a considerable rate in the coming years.
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The advanced research and development facilities and new product developments by the companies are supporting to address the demand for the breast imaging technologies industry. However, strict regulatory approval procedures, and unfavorable reimbursement policies in the developing countries are posing a challenge for the growth of the breast imaging technologies market.
Breast cancer is the most common cancer in women. According to International Agency for Research on Cancer (IARC) and World Health Organization (WHO), globally, approximately 1.7 million new cases of breast cancer were diagnosed in 2012. As the incidence of breast cancer is increasing significantly, development of improved technology with less radiation exposure is also expected to support the growth of the breast imaging technologies market.
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Geographically, North America will be leading the global breast imaging technologies market in the coming years due to technological advancement in breast imaging, rising awareness of early detection of breast cancer and increasing government initiatives and funding in research and product innovations in the region. Moreover, Asia-Pacific is the fastest growing region in the global breast imaging technologies market. The major reasons for the fastest growth in the region are increasing healthcare expenditure, increasing incidence and prevalence of breast cancer cases, increasing government initiatives and investment in breast imaging technologies, and improving healthcare infrastructure in the region. Moreover, the breast imaging technologies market is growing due to increasing awareness about women health in the emerging countries, such as India and China, of Asia-Pacific region.
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Some of the companies operating in the breast imaging technologies market are Toshiba Corporation, Aurora Imaging Technologies, Dilon Technologies, Inc., Gamma Medica, Inc., Sonocine, Inc., Siemens Healthcare, Philips Healthcare, GE Healthcare, Dune Medical Devices, U-Systems, Inc., and Hologic, Inc.
Estrogen Receptor-Positive Breast Cancer Pipeline Analysis, 2017
The study analyzed that the estrogen receptor positive breast cancer pipeline comprises approximately 74 drug candidates, of which nine products are in Phase III, 16 products in Phase II, 18 products in Phase I, and three products are in Pre-Clinical stage. The development of 14 ER+ breast cancer drug candidates was found to be inactive, and 14 products were discontinued. ER+ breast cancer is the most common type of breast cancer diagnosed and refers to the cancer cells that have receptors on their surface to bind with estrogen. Breast cancer is a syndrome that affects the breast tissues. In breast cancer, cells in the breast grow in an uncontrollable manner and form tumor, which can be felt as a lump or can be viewed under x-ray. Invasion of new therapeutic agents, such as gene therapy, cell therapy and monoclonal antibodies are expected to provide an effective and concrete treatment for the disease, more in the light of the new technologies available.
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Insights on pipeline analysis
As per the findings of the research, a major share of ER+ breast cancer pipeline drug candidates are being developed to be administered by oral route and rest by intravenous route and subcutaneous route. Most of the therapeutic candidates are being developed to be administered by oral route due to high patient compliance.
Several companies are developing ER+ breast cancer drug candidates in different phases. Novartis AG, Syndax Pharmaceuticals, Tesaro, Inc. and others have their ER+ breast cancer drug candidates in Phase III stage of development. Novartis AG has three drug candidates in Phase III stage and two drug candidates in Phase I clinical stage.
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Some of the key players developing drugs for Estrogen Receptor-Positive (ER+) breast cancer are Chipscreen Biosciences, Ltd., Eli Lilly & Company, Genentech, Inc., Novartis AG, Ipsen, Syndax Pharmaceuticals, Inc., Tesaro, Inc Astellas Pharma Inc., AstraZeneca plc, and Bayer AG.
Automotive Sunroof Market Trends, Size, Development and Forecast to 2022
The global automotive sunroof market was valued at $4,924.5 million in 2015, and it is expected to grow at a CAGR of 10.9% during 2016 - 2022. The factors driving the growth of the global market includes growing need to control light inside vehicle, growing demand for premium cars, and greater glass surface area in automobiles, including larger sunroofs. Additionally, the development of technology for reducing cost and expanding functionality of sunroof glasses and increasing consumer preference towards automotive sunroof vehicles in developing nations are expected to further propel the global demand of automotive sunroof.
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Automotive sunroof refers to any roof opening in vehicle, such as one with a retractable metal panel. Modern sunroof consists of around 200 parts, and vehicle maker now use them and other roof system to help differentiate product offering to customers. Consumers now expect an increasingly high level of comfort in their cars, particularly where air conditioning and sun roof are concerned. Such equipment is no longer the exclusive domain of luxury cars. As the market is becoming increasingly competitive, vehicle makers are using sunroofs and other roof systems to help differentiate the product offering to customers. The demand for sunroof as an after sales market has also contributed to the growth of the global automotive sunroof market. The growing alternative fuel vehicle segments have forced the automotive innovators to develop sunroofs with built-in solar cells, which provide power to vehicles. The preference of car involving a sunroof is a major trend witnessed in the automotive sunroof market during the last few years.
Among the various vehicle types, the premium cars held the major market share in the global automotive sunroof market. The high-income group prefers premium cars owing to their aesthetic looks, convenient travel experience, and it also resembles the statues symbol in the society. Now-a-days sedan cars are extensively using sunroof systems, as the manufacturer are targeting middle income group people and also the convertible sunroofs are gaining popularity among the individuals. Thus, the sedan car segment is expected to witness the fastest growth in the global automotive sunroof market during the forecast period.
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Some of the major companies operating in the global automotive sunroof market include Webasto SE, Johnan America, Inc., Automotive Sunroof Company, Nippon Sheet Glass Co. Ltd., Yachiyo Industry Co., Ltd., Corning Inc., Meritor Inc., Aisin Seiki Co., Ltd., Inteva Products, LLC, and Inalfa Roof Systems Group B.V.
3D Bioprinting Market Size, Analysis, Growth and Demand Forecast to 2022
The global 3D bioprinting market was valued at $98.6 million in 2015, and it is expected to grow at a CAGR of 35.9% during 2016 - 2022. The growth of the global market is largely driven by increasing large demand of tissues and organs for transplantation and the innovations and advancements in technology for 3D bioprinting. A large number of people across the globe are waiting for organ or tissue transplant, due to the huge gap in demand for organs transplant and donors. This has created huge traction in the 3D printing industry for developing live tissues and organs. Different companies along with academic institutes and laboratories are investing huge capital for 3D bioprinting research and development. Some of the other factors driving the growth of the global market include increasing research and development activities and increasing compliance for 3D bioprinting in drug discovery processes. Growing stem cell research and increasing adoption of 3D bioprinting in cosmetic industry are expected to create ample growth opportunities for the global market. However, the high cost of 3D bioprinting, lack of skilled professionals and stringent regulatory processes are the key barriers for the growth of the global market.
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Among the 3D bioprinting technologies, the pneumatic extrusion based 3D bioprinting would witness the fastest growth during the forecast period. Increasing adoption of pneumatic extrusion based 3D bioprinting in the industry and its high resolution are the major factors driving the growth of the pneumatic extrusion based 3D bioprinting market. Syringe based 3D bioprinting contributed the largest revenue in the global market in 2015. The technology along with pneumatic extrusion based technology accounted for over 60% share in the global market in 2015.
North America accounted for the largest share in the global market in 2015, owing to the technological advancements and innovations, and increasing research and development activities. The U.S. contributed largest revenue to the North American as well as global 3D bioprinting market. The country is expected to remain the largest market for 3D bioprinting globally during the forecast period. The huge capital investments along with the significant development in 3D bioprinting are the key driving factors of the U.S. 3D bioprinting market.
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Some of the players operating in the global market include Organovo Holdings, Inc., CELLINK, EnvisionTEC, BioBots, Cyfuse Biomedical K.K., Aspect Biosystems Ltd., 3D Bioprinting Solutions, Ourobotics, Advanced Solutions, Inc., GeSiM, Bio3D Technologies, 3Dynamic Systems Ltd., Nano3D Biosciences, Inc., Poietis, regenHU Ltd., and Aerotech Inc.
Programmed Death-1 (PD-1) and Programmed Death Ligand-1 (PD-L1) Inhibitors Pipeline Analysis and Demand Forecast to 2025
The global programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) inhibitors market is valued at an estimated $4,926.4 million in 2016, and it is expected to grow at a CAGR of 23.4% during 2017 - 2025.
The growth of the global market is largely driven by the increased investment and funding, strong pipeline, and improved safety and efficacy. BGB-A317, a Phase I therapeutic candidate of BeiGene Ltd., gained $75 million funding to continued development of targeted oncology candidate. PD-1 and PD-L1 inhibitors are applicable to a wider range of tumor types such as advanced or metastatic non-small cell lung cancer, renal cancer, melanoma and others. These inhibitors lower the rate of severe toxicities and immune-mediated side-effects. These are also convenient to administer, and yield a good response rate of any single-agent immunotherapy. This creates huge traction in pharmaceutical industry to develop PD-1 and PD-L1 inhibitors for treatment of different types of cancer.
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PD-1 and PD-L1 inhibitors are highly growing immunotherapies that are being used in oncology therapy area. The pipeline of PD-1 and PD-L1 inhibitors is enriched with 47 drugs and there are approximately 245 active clinical studies. Currently, durvalumab from Astrazeneca and atezolizumab from Roche are among the most promising molecules in the pipeline, in terms of efficacy and safety. These molecules are in Phase III stage and expected to be launched in the coming years for the treatment of non-small cell lung cancer. There are many drugs in early stage of pipeline; thus, making PD1 and PDL1 inhibitors market very lucrative.
Among the different marketed PD-1 and PD-L1 inhibitor drugs, the largest revenue globally was generated from the sale of Opdivo in 2016. The global demand of Tecentriq is expected to witness high growth, primarily driven by the lack of approved competitor PD-L1 inhibitors drugs and high prevalence of urothelioma cancer.
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Some of the key players operating in the global market include Merck & Co., Inc., Bristol-Myers Squibb Company, AstraZeneca plc, Pfizer Inc., F. Hoffmann-La Roche AG, Novartis AG, Regeneron Pharmaceuticals, Inc., Ono Pharmaceutical Co., Ltd., and Merck KGaA.
Personal Protective Equipment Market Analysis, Size, Growth and Forecast to 2020
The stringent regulations related to occupational health and safety is the key growth driver for the global personal protective equipment market. The increasing consumer awareness about personal safety at workplace is another important factor for the growth of this market. The companies around the world are focusing on employee safety, due to up surge in workplace fatalities. The hand protection equipment dominates the product segment of the global personal protective equipment market; however protective clothing is expected to become the largest product segment by 2020. Based on industry type, manufacturing industry dominated the market in 2014.
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The personal protective equipment includes products related to the protection of eye, face, head, foot and legs, and hand and arms. The hazards of different types caused by falling of objects, colliding with sharp edges, interaction with chemicals, flying sparks and several others are caused at workplaces. Several codes of regulations (CFR) have been laid down by the Occupational Safety and Health Administration (OSHA), which states the employers’ liability to protect their employees from workplace hazards causing injuries. The major CFRs include eye and face protection, head protection, foot protection, electrical protective equipment, and hand protection. The non-compliance of such regulations and codes attract huge penalties to the employers. The prevalent regulations and certifications related to protection at workplace are issued by OSHA, American National Standards Institute (ANSI), and CSA Group.
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The U.S. is the major market for personal protective equipment globally. The major markets in Europe include Germany, the U.K., France, and Russia. The key markets in Asia-Pacific include China, India, and Japan. The increasing industrialization in Asia-Pacific, owing to high population growth is expected to significantly boost the growth of the market for personal protective equipment in the region. The emerging countries, such as Vietnam, Indonesia, and Brazil are expected to provide growth opportunity for the global personal protective equipment market.
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The global personal protective equipment market is fragmented with presence of large number of regional players. The major competitors in the global personal protective equipment market include 3M Company, Honeywell, Alpha Pro Tech Limited, Ansell Ltd., Avon Rubber PLC, JAL Group Italia SRL, COFRA SRL, Uvex Safety Group, Rock Fall Limited.
Farm Equipment Market Analysis, Size, Growth and Demand Forecast to 2020
The increasing population has been propelling the demand for food items, which is consequently driving the growth of the global farm equipment market. The up gradation in the technology, increasing government subsidies on agricultural machineries, growth of precision farming and easily available credit schemes from financial institutions are encouraging the growth of the global market. Asia-Pacific accounted for the largest share in the global market in 2014, owing to its large population that translates into demand for crops. Among the various types, the tractors segment dominated the global farm equipment market in 2014.
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Farm equipment includes machineries used for the production and maintenance of crops and agricultural livestock. Tractors are one of the essential farm equipment that serves several purposes in agriculture, including plowing, harrowing, and transportation of agricultural products. The harvesting equipment includes combine harvesters and threshers. The modern tractors are equipped with global positioning systems (GPS) and on-board computers. The expansion of precision farming has been positively impacting the growth of the farm equipment market. The farmers are up grading their traditional farm equipment with more advanced alternatives. The advent of do-it-yourself (DIY) repair tractors have also reduced the cost and hassle of tractor repairing, thus providing more comfort to farmers.
The government in different countries has been extending several subsidy programs to encourage farmers in their agricultural ventures. In 2004, China implemented subsidy policy for agricultural machineries, which increased over the years and now includes 12 agricultural categories. Around 175 types of agricultural machineries were subsidized by the Chinese government in 2015. During 2004 – 2012, the Chinese government dedicated $12 as subsidy for agricultural machineries. In order to promote food security in the country, the Chinese government has announced a subsidy scheme in 2015 for farm equipment, under which about 30% of the sales price of such equipment will be subsidized. The staple crop growers in the country, including sugar and cotton farmers will be prioritized.
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The major farm equipment markets in Europe include Germany, France, Italy, the U.K., Russia, Turkey, and Poland. Whereas the key markets in Asia-Pacific include China, India, Japan, and Australia. The major companies in the global market include Alamo Group Inc., AGCO Corporation, Deere & Company, Daedong industrial Company Limited, Escorts Group, and Netafim.
