Hospital Infection Therapeutics Market Size, Development, Growth and Forecast to 2023
The hospital infection therapeutics market is increasing at a significant rate, due to high susceptibility of neonatal population in healthcare setting and high occurrence of numerous hospital infections. Increasing incidences of hospital infections, high number of pipeline drug molecules for specific treatment of healthcare associated infections and high unaddressed needs in most of the countries are some of the factors providing ample opportunities for the hospital infection therapeutics market to grow in the coming years.
North America leads the hospital infection therapeutics market followed by Europe. The North America hospital infection therapeutics market leads, due to improved healthcare awareness, high ratio of hospitals as compared to population of the region, increasing count of multi drug resistant microbial pathogens and increase in aging population of the region. Asia-Pacific is growing with an exponential rate, due to increased incidences of hospital infections and high demands of therapeutic drugs in the emerging countries such India and China.
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Hospital acquired infections are caused produced by viral pathogens, fungal and bacterial. Most of the hospital infections crop up from intensive care units. Varied range of hospital infections are being treated by various antimicrobial drugs. The patients staying in the hospitals develop several infections during their treatment. . The infections are known as hospital-acquired infections or hospital infections. The hospital acquired infections spread in the hospitals, rehabilitation centers, outpatient surgery centers, nursing homes and dialysis centers.
Some of the pipeline drugs available in the market for hospital acquired infections are MK-3415A, Amikacin Inhale, Oritavancin, Surotomycin, Ceftolozane, Dalvance, Plazomicin, Eravacycline, Tedizolid, Delafloxacin, and CAZ AVI. In 2011, according to the centers for disease control and prevention, around 1.6 million hospital acquired infections have been reported from all types of bacteria in US every year. Additionally, in 2013 about 4 million patients were identified with hospital acquired infections in Europe.
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Some of the competitors in the hospital infection therapeutics market are: Cubist Pharmaceuticals, Inc., Actavis PLC, Johnson & Johnson Services, Inc., Bayer AG, GlaxoSmithKline PLC, Bristol-Myers Squibb Company, Merck & Co., Inc., AstraZeneca PLC, Pfizer, Inc. and Sanofi.
Bioinformatics Market Analysis, Size, Development, Growth and Forecast to 2023
The introduction and adoption of cloud computing and nanopore technology are expected to offer numerous opportunities in the global bioinformatics market. The nanopore technology has been projected for getting used in the study of crop science, deoxyribonucleic acid (DNA), ribonucleic acid (RNA), proteins and small molecules with a range of applications in personalized medicine, and scientific research.
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Bioinformatics is a discipline that deals with the retrieval, storage, processing, management and analysis of organic information through computational techniques. Bioinformatics plays an important role in drug innovation and improvement. The involvement of bioinformatics in storing, retrieving, analyzing and forming biological information helps in efficiently managing enormous database associated with drug innovation and development.
The global bioinformatics market can be broadly segmented on the basis of applications, products and services, sectors and geographies. On the basis of products & services the bioinformatics market can be broadly bifurcated into bioinformatics platforms, bioinformatics knowledge management tools and bioinformatics services. The bioinformatics knowledge management tools segment can be further divided into specialized tools and generalized tools. The bioinformatics platforms are further sub-divided into sequence alignment platforms, sequence analysis platforms, structural & functional analysis platforms and sequence manipulation platforms. The bioinformatics services segment is again segmented into database & management, sequencing services and data analysis.
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North America dominated the global bioinformatics market in 2013, by holding approximately 42% of the market share. The availability of encouraging government support in terms of funding and large number of research initiatives carried out in the region are some of the factors responsible for worldwide dominance of the region. The Asia-Pacific bioinformatics market is projected to be the fastest growing regional market in the forecast period. High availability of trained labors in countries such as, China and India with low labor costs has inspired manufacturers to stick upon contract research outsourcing strategies for limiting costs, which has enormously contributed to the growth of Asia-Pacific bioinformatics market.
Some of the key competitors within the global bioinformatics market include Tripos, LP, Affymetrix, Inc, Agilent Technologies, Illumina, Inc., Helicos Biosciences Corporation, IBM Life Sciences, Thermo Fisher Scientific Inc, Rosetta Inpharmatics LLC, Celera and others.
Amyotrophic Lateral Sclerosis Pipeline Analysis 2017 - Clinical Trials & Results, Patent and Other Developments
The study analysed that the Amyotrophic lateral sclerosis pipeline comprises of 69 drug candidates, of which one drug candidate is in Phase III stage, 16 drug candidates are in Phase II stage, nine drug candidates are in Phase I stage, 32 drug candidates are in Pre-Clinical stage, five candidates are inactive and six drug candidates are in discontinued stage. Amyotrophic lateral sclerosis is a neurodegenerative disorder in brain and spinal cord, the progression of the disease can further lead to muscles getting enough nourishments, which can further cause atrophy of the muscles. Amyotrophic Lateral Sclerosis occurs mostly in the lateral region of the body, in which spinal cord reflexes are too intense. This can also lead to scarring and hardening of the muscles into that region. Various new therapies and advanced technologies are driving the growth of Amyotrophic lateral sclerosis pipeline.
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As per the findings of the research, around 31.0% of drug candidates for the treatment of amyotrophic lateral sclerosis pipeline are being developed to be administered by oral route, 4.0% by intravenous route, 48.0% are not disclosed and 17.0% are to be administered by other routes which includes subcutaneous, intraperitoneal, sublingual, inhalation and intramuscular.
The research also found that various companies have collaborated for the development of amyotrophic lateral sclerosis pipeline. In March 2013, Dainippon Sumitomo Pharma Co., Ltd. signed a research, development and commercial licensing agreement with Edison Pharmaceuticals, Inc. for EPI-743 and EPI-589 in Japan. Dainippon Sumitomo Pharma Co., Ltd. received exclusive research, development and commercial rights in Japan for EPI-743 and EPI-589. Edison Pharmaceuticals, Inc. received $35.0 million in an upfront payment and $15.0 million as research and development support fee. In addition, Edison Pharmaceuticals, Inc. also received $10.0 to $35.0 million in milestone payments per indication associated with successful development. After the launch, Edison Pharmaceuticals, Inc. received royalties based on sales amounts and up to $460.0 million in milestone payments in accordance with sales goals.
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Many companies are developing Amyotrophic lateral sclerosis drug candidates in different phases. Cytokinetics, Inc., AB Science, F. Hoffman La-Roche AG, FlexPharma, Inc., Orion Corporation, Omeros Corporation, Genervon Biopharmaceuticals, LLC, Edison Pharmaceuticals, Inc., BrainStorm Cell Therapeutics, Inc. and various other companies have their Amyotrophic lateral sclerosis drug candidates in different stages of development. Cytokinetics, Inc. has drug candidate in Phase III clinical stage.
Some of the key players developing drugs for Amyotrophic lateral sclerosis include FlexPharma, Inc., Orion Corporation, Genervon Biopharmaceuticals, LLC, Orphazyme ApS, Edison Pharmaceuticals, Inc., BrainStorm Cell Therapeutics, Inc. and Cytokinetics, Inc.
Next-Generation Sequencing Market Size, Development, Growth and Forecast to 2023
The global next-generation sequencing market is growing significantly due to advances in next-generation technologies, increasing scientists and researchers’ compliance for next-generation sequencing, and low cost of next-generation sequencing methods compared to conventional sequencing methods in the industry. The unexplored next-generation sequencing market in emerging economies and increasing focus for the development of personalized medicine are creating opportunities for the global next generation sequencing market to grow at a considerable rate in the coming years. The advanced research and development activities by the major players are propelling the demand for cost effective and efficient next-generation sequencing platforms. However, interpretation of large volume of complex sequencing data through next-generation sequencing platforms is a major challenge in global next-generation sequencing market.
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Usage of nanopore sequencing technology for the development of next-generation sequencing platforms is a trend in global next-generation sequencing market. Next-generation sequencing provides high throughput sequencing to researchers and scientists with high specificity and speed, and reduced cost. Conventional sequencing methods, such as Sanger method that are slower, expensive and require large amount of template DNA next-generation sequencing, has overcome these limitations with more accurate results.
The global next-generation sequencing market is categorized as technology type, sequencing workflow, applications, and end-users. Based on technology type, the next-generation sequencing market is categorized as pyrosequencing, ion-semiconductor sequencing, sequencing by synthesis, single molecule realtime sequencing, and sequencing by ligation. The sequencing by synthesis segment leads the global next-generation sequencing market. Based on sequencing workflow, the next-generation sequencing market is categorized as next-generation pre-sequencing, next-generation sequencing platforms, and next-generation sequencing services.
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Based on applications, the next-generation sequencing market can be categorized as diagnostics, drug discovery, animal and agriculture research, personalized medicine, and others. End-users of next-generation sequencing include academic and research institutes, biopharmaceutical and biotechnology companies, hospitals, and others. Academic and research institutes lead the global next-generation sequencing market.
Some of the major players operating in the global next-generation sequencing market are Agilent Technologies, Inc., F. Hoffmann-La Roche AG, Biomatters, Ltd., GATC Biotech AG, Illumina, Inc., Thermo Fisher Scientific, Inc., Pacific Biosciences, Oxford Nanopore Technologies, Ltd, Macrogen, Inc. among others.
Healthcare BPO Market Analysis, Size, Development, Growth and Forecast to 2023
The global healthcare business process outsourcing market is witnessing significant growth, due to technological advancements in healthcare IT sector and increasing demand for reducing healthcare costs. The tenth revision of International Statistical Classification of Diseases and Health Related Problems (ICD-10), emergence of biologics and massive unexplored healthcare BPO market in the emerging economies are creating ample opportunities for the growth of the global healthcare BPO market. Healthcare reforms across the globe and adoption of healthcare BPO by major pharmaceuticals, biopharmaceuticals and biotechnology companies are supporting the demand of cost effective and improved healthcare system.
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Healthcare BPO is the practice of outsourcing business operations by healthcare providers, payers and organizations. Healthcare BPO has several advantages, such as availability of skilled workforce at low cost, reduction in training and administrative costs, and high profitability for healthcare organizations, payers, and providers. In addition, healthcare BPO also improves the quality of patient care, while reducing the investment required for infrastructure.
The global healthcare BPO market is segmented into pharmaceuticals outsourcing, providers outsourcing, and payers outsourcing. The pharmaceutical outsourcing segment leads the global healthcare BPO market. The pharmaceuticals outsourcing segment can be further categorized as contract manufacturing organizations (CMO), contract research organizations (CRO) and non-clinical services. The healthcare providers outsourcing segment includes medical transcription, medical billing, medical coding, and finance and accounts. The healthcare payers outsourcing segment includes customer care and member services, HR services, claims processing, and finance and accounts.
Some of the factors driving the growth of the global healthcare BPO market are increasing healthcare costs, advancement in the healthcare IT technology, lack of skilled professionals and increasing demand for improved healthcare. In addition, the high cost associated with R&D and manufacturing of drugs and reduced productivity is compelling the major pharmaceuticals companies to outsource their business processes. However, data security and privacy concerns, unforeseen costs, and difference in the regulatory processes within different countries are restraining the growth of the global healthcare BPO market.
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Some of the major players operating in the global healthcare BPO market are Accenture, Tata Consultancy Services (a part of Tata Group), Genpact, Boehringer Ingelheim GmbH, Cognizant, Charles River Laboratories International Inc., Covance Inc., Infosys Limited, Lonza Group Ltd. and Quintiles Inc.
Contract Research Organization (CRO) Market Analysis, Size, Growth and Forecast to 2023
The increasing R&D investments from pharmaceutical companies and extensive drug pipelines for the treatment of various chronic diseases, such as immunological disorders, metabolic disorders, and neurological disorders, are the predominant growth drivers for the global contract research organization market. Additionally, the increasing outsourcing of pharmaceutical and biopharmaceutical R&D activities, high failure rate of drug clinical trials, and low cost of conducting clinical trials in emerging countries are also driving the growth of the market. The growing numbers of mergers and acquisitions is a key trend observed in the market. Among the various end-user segments of CRO, the last-stage development service accounted for the largest and fastest growing segment in the global market.
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CROs provide support and services in form of research facilities outsourced on contract basis to life sciences, pharmaceutical, and medical device industries. The major services offered by CROs include preclinical research, biologic assay development, biopharmaceutical and pharmaceutical development, commercialization, clinical trials management, and clinical research. These organizations also provide support to research organizations, academic institutes, and government organizations.
The stringent regulation for the approval of pharmaceutical and biopharmaceutical drugs is restraining the growth of the global CRO market. Moreover, the lack of skilled research professionals is also hindering the growth of the market, especially in the developing countries, such as India and China.
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North America and Europe are the major markets, due to increasing prevalence of chronic diseases, and improved research infrastructure in these regions. The U.S. followed by Canada, is the largest market for CRO in North America. Whereas, the U.K., Germany, and France are some of the major countries holding significant share in the European market.
Some of the major players operating in the global CRO market include WuXi AppTec, Viva Biotech, Ltd., TCG Lifesciences Pvt. Ltd., Sygnature Discovery Ltd., Sundia MediTech Company Ltd., Shanghai Medicilon Inc., ChemPartner, Selvita S.A., Selcia Ltd., Scynexis Inc., Ricerca Biosciences LLC, Pharmaron Inc., Nanosyn Inc., Jubilant Biosys Ltd., Hutchison MediPharma Ltd., Graffinity Pharmaceuticals GmbH, Albany Molecular Research Inc., Argenta Discovery Ltd., Aptuit LLC, Asclepia MedChem Solutions, AsisChem Inc., Caliper Life Sciences, CreaGen Biosciences Inc., Chemical Diversity Inc., BioDuro, Emerald Biostructures, and Jubilant Biosys Ltd.
Nuclear Imaging Equipment Market Trends, Size, Development and Forecast to 2023
According to the study, the global nuclear imaging equipment market is likely to grow significantly during the forecast period, due to rising prevalence of cancer and cardiovascular diseases, increasing geriatric population and increasing prevalence of neurological disorders. In addition, rising healthcare expenditure and launch of technologically advanced products contribute to the growth of the overall market. High cost of imaging techniques is the key factor restraining the global market growth.
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Insights on market segments
As per the findings of the research, based on products, the SPECT is the largest category, in the global nuclear imaging equipment market. Hybrid SPECT, further forms the larger part of the global market for SPECT. Oncology has been the largest application of the global market, followed by cardiology, neurology and others. Hospitals has been the largest end user of nuclear imaging equipment, followed by diagnostic centers, research institutes and others.
North America stands as the largest nuclear imaging equipment market
Geographically, North America has been the largest market for nuclear imaging equipment, with the U.S. being the largest contributor to the regional market. Increasing prevalence of cancer and cardiovascular diseases and presence of technological advanced products has been driving the growth of the North American market for nuclear imaging equipment. In Europe, Germany has been the largest contributor to the market for nuclear imaging equipment, followed by France and the U.K. The market is expected to witness the fastest growth in Asia-Pacific, during 2017 - 2023, owing to increasing cases of cancer, cardiovascular diseases, neurological disorders and increasing geriatric population.
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Key players in the nuclear imaging equipment market
Some of the key players in the global nuclear imaging equipment market include Siemens AG, GE Healthcare, Philips Healthcare, Digirad Corporation and Neusoft Medical Systems Co., Ltd., Cannon Inc., DDD Diagnostics, CMR Naviscan Corporation, SurgicEye GmbH and Mediso Medical Imaging Systems Ltd.
